ketamine and pulmonary hypertension

Ketamine, frequently utilized in anesthesia and pain management, may exert certain influences on individuals with pulmonary arterial hypertension (PAH). Typically, ketamine can cause an elevation in pulmonary artery pressure, potentially worsening the condition for PAH patients.

Ketamine, by stimulating adrenergic receptors, might lead to an accelerated heart rate and increased blood pressure, thus augmenting the cardiac workload. In the context of PAH, this could further amplify pulmonary artery pressure, exacerbating symptoms like dyspnea and chest pain. Moreover, ketamine can induce bronchodilation, which may provide temporary relief from the breathing difficulties experienced by PAH patients. However, this effect is often transient and could come with additional risks.

Hence, for individuals with PAH, the use of ketamine should be approached with caution. It is advised to use it under a physician's supervision, adhering to medical prescriptions and avoiding self-administration without guidance. Patients should also monitor their responses to ketamine and seek medical attention promptly if they experience discomfort.