metformin for hypertension

Metformin, a frequently utilized oral antihyperglycemic agent, is typically not endorsed for the treatment of hypertension. Despite its notable efficacy in managing blood glucose levels, its impact on reducing blood pressure is limited and it is not considered a first-line therapy.

Mechanistically, metformin lowers blood glucose primarily by curtailing hepatic glycogen production and enhancing insulin sensitivity. While research indicates potential benefits of metformin for certain hypertensive patients, such as those with comorbid diabetes or obesity, its hypotensive effects are generally mild and it is often used in conjunction with other specialized antihypertensive medications. Moreover, metformin may induce side effects like gastrointestinal discomfort, potentially restricting its use in hypertension management.

For individuals with hypertension, it is advisable to select appropriate antihypertensive medications under a physician's supervision and to adhere to the prescribed treatment regimen. Additionally, lifestyle modifications are crucial for controlling hypertension, encompassing a healthy diet, regular exercise, smoking cessation, and alcohol moderation. In cases where patients exhibit abnormal blood sugar levels, physicians may consider incorporating metformin into the treatment regimen, though this decision should be tailored to the individual's specific health profile. Ultimately, in managing hypertension, it is imperative to follow the advice of healthcare professionals and avoid the indiscriminate use of any medication without proper guidance.