pvr in pulmonary hypertension

Pulmonary vascular resistance (PVR) is pivotal in pulmonary arterial hypertension (PAH), serving as a critical metric for gauging the severity of PAH. Elevated PVR can impose an increased workload on the right ventricle, potentially leading to heart failure. Thus, comprehending the normal PVR range and its alterations in PAH is essential for both diagnosis and therapeutic management.

The normal PVR range typically falls between 1 to 2 Wood units. Deviation from this range may indicate the presence of PAH symptoms. In the early phases of PAH, a mild PVR increase could stem from various factors, such as pulmonary vasoconstriction, inflammation, or thrombosis. As the condition advances, substantial PVR elevation is often linked to pulmonary vascular remodeling, possibly a consequence of sustained hypertension causing vessel wall thickening and fibrosis. Moreover, certain genetic and environmental influences might contribute to an abnormal rise in PVR.

For individuals with PAH, consistent PVR monitoring is imperative. Should your PVR deviate from the norm, adhere to your physician's treatment recommendations and conduct regular follow-ups to track the progression of your condition. Bear in mind that any pharmacological interventions should be directed under professional medical supervision; self-adjustment of medication dosage or discontinuation is strongly discouraged.