pulmonary hypertension cirrhosis

Pulmonary arterial hypertension (PAH) co-occurring with liver cirrhosis is an uncommon but critical health issue, impacting two vital organ systems: the heart and the liver. Symptoms such as dyspnea, fatigue, and weight loss may arise, with severe cases potentially being life-threatening.

PAH is characterized by elevated blood pressure in the pulmonary arteries, increasing the heart's workload to pump blood through the lungs. Chronically, this can result in right ventricular hypertrophy and dysfunction. Cirrhosis, meanwhile, is marked by the replacement of healthy liver tissue with fibrous scar tissue, impairing liver function. When these two conditions coexist, they can exacerbate each other's symptoms and progression. For instance, cirrhosis may lead to portal hypertension, which can affect both cardiac and pulmonary function; conversely, PAH might cause inadequate blood supply to the liver, worsening liver damage.

Patients with PAH and liver cirrhosis must manage their condition carefully to prevent exacerbation and avoid triggers. This includes adopting a healthy diet, limiting sodium intake to alleviate cardiac strain, and refraining from alcohol and tobacco use. Regular health monitoring and adherence to medical treatment are crucial. Patients should be vigilant about any changes in their health and seek medical help without delay if they experience discomfort. With a physician's guidance, making informed adjustments to lifestyle and medication regimens can effectively manage the disease and enhance the quality of life.