cialis and pulmonary hypertension

Sildenafil, used for the treatment of pulmonary arterial hypertension, typically has a role in alleviating symptoms and enhancing the quality of life for patients. However, its therapeutic efficacy and safety profile must be evaluated and closely monitored under medical supervision.

Sildenafil functions by inhibiting phosphodiesterase-5 (PDE-5), which leads to the relaxation of vascular smooth muscle and a consequent reduction in pulmonary arterial pressure. In patients with mild to moderate pulmonary arterial hypertension, sildenafil may contribute to improved exercise tolerance and cardiac function. Nevertheless, for those with severe or complex conditions, monotherapy with sildenafil might not be adequate for disease control, necessitating the combination with other medications or the adoption of more aggressive therapeutic strategies.

Patients undergoing treatment with sildenafil for pulmonary arterial hypertension should vigilantly monitor their responses and potential side effects, and engage in regular necessary examinations. It is crucial to adhere to the physician's instructions and refrain from adjusting the dosage or discontinuing the medication without guidance. Additionally, maintaining a healthy lifestyle, including smoking cessation, alcohol moderation, and regular physical activity, can further contribute to the amelioration of pulmonary arterial hypertension symptoms and outcomes.