hypertensive heart disease with chronic kidney disease

Hypertensive heart disease coexisting with chronic kidney disease is a complex condition affecting both the cardiovascular and renal systems, typically characterized by a progressive decline in the function of the heart and kidneys. Poor blood pressure management is closely associated with the progression of this disease, which can result in severe outcomes such as heart failure and renal insufficiency.

Upon detailed examination, the effects of hypertension on the heart are initially evident in the form of left ventricular hypertrophy, an adaptive response to increased blood pressure. Prolonged exposure to excessive pressure can lead to myocardial fibrosis, chamber dilation, and ultimately, the development of heart failure. Concurrently, hypertension can injure the renal microvasculature, causing glomerulosclerosis and interstitial fibrosis, which impairs the kidney's filtration capacity and can lead to chronic kidney disease. As the disease advances, patients may present with symptoms like proteinuria, hematuria, and edema, with a gradual decline in renal function that, in severe cases, can progress to end-stage renal disease requiring dialysis or kidney transplantation.

For individuals with hypertensive heart disease and chronic kidney disease, it is crucial to manage blood pressure and alleviate renal strain through a low-salt diet, regular physical activity, and maintaining a healthy weight. Additionally, routine monitoring of blood pressure, renal function, and urinalysis is imperative. In terms of pharmacological treatment, adherence to medical guidance is essential; self-adjustment of medication dosage or cessation of treatment should be avoided to prevent exacerbation of the condition. Should symptoms such as chest tightness, shortness of breath, or lower limb edema arise, prompt medical attention is advised.