high renin hypertension

Hypertension with high renin activity arises from an overactive renin-angiotensin system, leading to increased blood pressure. Renin, an enzyme released by the kidneys, converts angiotensinogen in the bloodstream to angiotensin I, which then transforms into angiotensin II—a potent vasoconstrictor that can elevate blood pressure. Consequently, excessively high renin levels can result in persistent hypertension.

Potential causes of high-renin hypertension encompass kidney diseases, renal artery stenosis, and endocrine disorders. The treatment typically targets the underlying cause, such as pharmaceutical interventions to inhibit the renin-angiotensin system or surgical procedures to address renal artery stenosis. Additionally, patients are advised to modify their lifestyle, including reducing salt intake, adopting a healthy diet, and engaging in moderate physical activity.

For individuals with high-renin hypertension, regular blood pressure monitoring and treatment under a physician's guidance are essential. Moreover, it is crucial for patients to adhere to their doctor's recommendations, manage their work-life balance effectively, and avoid excessive fatigue and stress to mitigate the risks associated with hypertension.