lithium and hypertension

The association between lithium and hypertension is generally characterized by the potential for lithium therapy to raise blood pressure levels. Lithium is frequently prescribed for psychiatric conditions such as bipolar disorder, while hypertension denotes a consistently high pressure within the blood vessels as blood circulates.

A closer look at the mechanism suggests that lithium might indirectly affect blood pressure by altering the kidneys' sodium excretion. Retention of sodium can increase blood volume, which in turn can elevate blood pressure. Moreover, lithium could also impact vascular function by altering intracellular signaling pathways, thereby influencing blood pressure levels. It's important to note that not all patients on lithium therapy experience an increase in blood pressure, and the extent of any rise can vary significantly among individuals. Typically, mild to moderate elevations in blood pressure are more prevalent, although there have been rare reports of severe hypertension.

For patients undergoing lithium treatment, it is advisable to have regular blood pressure checks and to follow a physician's advice on lifestyle and dietary modifications to manage blood pressure. Patients should strictly adhere to the prescribed medication regimen and avoid any self-directed changes in dosage or discontinuation, which could lead to blood pressure fluctuations or other adverse effects. Should any concerns or discomforts arise, prompt medical consultation is recommended.