methotrexate hypertension

Hypertension associated with methotrexate is often linked to the medication's dosage and administration frequency. Methotrexate, frequently prescribed for certain cancers and autoimmune conditions like rheumatoid arthritis, can also cause blood pressure to rise.

Firstly, a slight increase in blood pressure might be attributed to methotrexate-induced reductions in folate levels within the body, which can be mitigated by folic acid supplementation. Secondly, moderate hypertension could be connected to methotrexate's effects on renal function, given the kidneys' crucial role in blood pressure regulation. Here, it may be necessary to monitor renal function and adjust the methotrexate dosage accordingly. Lastly, severe hypertension might stem from systemic inflammatory responses triggered by methotrexate, potentially necessitating its discontinuation and the exploration of alternative treatments.

For patients on methotrexate, regular monitoring of blood pressure and renal function is crucial. Should symptoms of elevated blood pressure arise, such as headaches, dizziness, or visual disturbances, immediate medical consultation is advised. Moreover, adhering to a physician's recommendations and making sensible lifestyle adjustments, including a healthy diet and regular physical activity, can aid in blood pressure management. Please remember that any medication use should be conducted under a doctor's supervision and not initiated without proper guidance.