uric acid and hypertension

There is a recognized association between uric acid levels and the risk of hypertension. Typically, elevated uric acid levels are associated with an increased likelihood of developing high blood pressure.

Uric acid, the end product of purine metabolism in humans, is primarily eliminated by the kidneys. Hyperuricemia arises when there is excessive production or insufficient excretion of uric acid, leading to increased levels in the bloodstream. This condition is not only closely linked to the development of gout but also poses potential risks to the cardiovascular system. Research indicates that elevated uric acid can induce endothelial dysfunction in blood vessels, enhancing their stiffness and resistance, which in turn can raise blood pressure. Furthermore, uric acid has the potential to activate the renin-angiotensin system, contributing to further blood pressure elevation. For patients with high uric acid levels, it is crucial to closely monitor blood pressure fluctuations and to implement appropriate interventions.

To address concerns regarding uric acid and hypertension, it is advisable to adopt a healthy lifestyle that includes a balanced diet, regular physical activity, and abstaining from smoking and limiting alcohol intake to help lower both uric acid and blood pressure levels. Additionally, the use of antihypertensive and urate-lowering medications may be necessary under a physician's supervision. It is imperative to adhere to medical guidance when using any medication and to avoid self-medicating without proper consultation.